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EVIDENCE GRADES TIPO-1 (Astrup 2008, PMID 18950853) reported -12.8 kg LS mean weight loss at 1.0 mg vs -2.2 kg placebo at 24 weeks

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A 2001 meta-analysis found rizatriptan 10mg to be more effective than the others at resolving all migraine symptoms by the two-hour mark, though sumatriptan came in second and third place at 100mg and 50mg, respectively.30 All three meds may induce similar side effects, but sumatriptan may pose the least risk of the most common adverse events, followed by zolmitriptan and then rizatriptan, respectively.31 32 33 So, while rizatriptan could be more effective at treating migraine, you may have a better overall experience with sumatriptan or zolmitriptan